MENOPAUSE PROGRAMS:
EFFICACY AND SAFETY

The decline in our capabilities as we age is closely related to the drop in our hormone levels.

Aging is not an inevitable process of functional loss and irreversible decline. The reduction in many of our hormone levels throughout life is associated with this aging process, and their controlled and properly prescribed replacement helps delay functional decline and the general deterioration linked to the passage of time.

At Neolife, we have spent many years caring for our patients’ health in our clinics. We have the highest level of training in hormonal optimization and the experience of thousands of treatments and satisfied patients behind us.

WHO SHOULD UNDERGO MENOPAUSE TREATMENT AT NEOLIFE?

Our programs are designed for:

WOMEN IN MENOPAUSE

WOMEN IN PERIMENOPAUSE with hormonal imbalances.

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Menopause represents a physiological stage in which the ovaries progressively lose their functional capacity, both in terms of follicular maturation and the production of key sex hormones essential for maintaining balance in the female body.

These changes may manifest with symptoms such as hot flashes, mood disturbances, sleep disorders, changes in body composition, vaginal dryness, discomfort during sexual intercourse, decreased sexual desire, and urinary symptoms.

In addition, less perceptible internal changes occur, including metabolic, cardiovascular, bone, and cognitive alterations that may impact health in the medium and long term.

For this reason, a comprehensive and personalized medical assessment is essential to understand this stage and preserve quality of life.

WHAT HORMONES DO WE SUPPLEMENT IN MENOPAUSE TREATMENTS?

ESTRADIOL

HORMONE

ESTRADIOL

SIGNS AND SYMPTOMS OF DEFICIT

  • Fatigue
  • Depression, low libido
  • Memory impairment
  • Hot flushes
  • Night sweats
  • Uterine or vaginal prolapse
  • Vaginal dryness, pain with sexual intercourse (dyspareunia), susceptibility to urinary tract infections, vaginitis, incontinence, etc.
  • Joint pain
  • Deep wrinkles
  • Dry mucous membranes
  • Dry skin
  • Chest drop
  • Skin paleness

SUSCEPTIBILITY TO DISEASES

  • Infertility
  • Premature aging
  • Osteopenia
  • Osteoporosis
  • Cardiovascular disease
  • Alzheimer’s disease

BIBLIOGRAPHY

  • 1. Jennifer L. Gordon, PhD1; David R. Rubinow, MD2; Tory A. Eisenlohr-Moul, PhD2; et al. Efficacy of Transdermal Estradiol and Micronized Progesterone in the Prevention of Depressive Symptoms in the Menopause Transition. A Randomized Clinical Trial.
  • 2. Gastlehner et al. Hormone Therapy for the primary prevention of chronic conditions in postmenopausal women: evidence report and systematic review for the US Preventives Task Force. JAMA. 2017;318(22):2234-49.
  • 3. Roelfsema F et al. Differential effects of estradiol and progesterone on cardiovascular risk factors in postmenopausal women. 2018 July;2(7):794-805.
TESTOSTERONE FOR WOMEN

HORMONE

TESTOSTERONE IN WOMEN

SIGNS AND SYMPTOMS OF DEFICIT

  • Depressive symptoms, anxiety, fears, irritability
  • Loss of assertiveness, authority and self-confidence.
  • Poor memory
  • Excessive sensitivity to problems, excessive preoccupations
  • Low stress tolerance
  • Aged appearance
  • Abdominal obesity
  • Low muscle mass
  • Permanent fatigue
  • Joint pain
  • Dry skin
  • Loss of libido, sensitivity and anorgasmia
  • Cellulite
  • Varicose veins

SUSCEPTIBILITY TO DISEASES

  • Depression
  • Anxiety
  • Joint problems
  • Osteoporosis

BIBLIOGRAPHY

  • 1. Glaser, R., & Dimitrakakis, C. (2013). Testosterone therapy in women: myths and misconceptions. Maturitas, 74(3), 230–234.
  • 2. Corona G, Rastrelli G, Maggi M. Diagnosis and treatment of late onset hypogonadism: systematic review and meta- analysis of TRT outcomes. Best Pract Res Clin Endocrinol Metab 2013;27:557-579.
PROGESTERONE

HORMONE

PROGESTERONE

SIGNS AND SYMPTOMS OF DEFICIT

  • Muscular and nervous tension
  • Irritability, aggressiveness
  • Premenstrual syndrome
  • Increased sensitivity to pain
  • Insomnia
  • Anxiety
  • Breast tenderness
  • Swollen breasts
  • Migraines associated with menstruation

SUSCEPTIBILITY TO DISEASES

  • Breast cysts
  • Breast cancer
  • Ovarian cysts
  • Endometriosis
  • Endometrial hyperplasia
  • Endometrial cancer
  • Myomas
  • Infertility
  • Preeclampsia and risk of miscarriage

BIBLIOGRAPHY

  • 1. Mirkin S. Evidence on the use of progesterone in menopausal hormone therapy. Climacteric. 2018 Aug;21(4):346-354.
  • 2. Harman SM et al. Is the estrogen controversy over? Deconstructing the Women´s Health Initiative study: a critical evaluation of the evidence. Ann N Y Acad Sci 2005 Jun; 1052:43-56.

START YOUR HORMONAL OPTIMIZATION TREATMENT AT NEOLIFE

1

COMPLETE THE PRELIMINARY QUESTIONNAIRE

Our medical team will review your preliminary questionnaire to determine whether you are suitable to begin treatment.

If appropriate, the initial phase will proceed, consisting of completing a detailed initial assessment questionnaire and submitting a blood test.

2

ATTEND AN INITIAL CONSULTATION

The initial assessment consultation with our medical team may be conducted in person or via telemedicine and lasts 30 minutes.

The questionnaire and blood test results will be reviewed, and a personalized Bioidentical Hormone Replacement Therapy (bHRT) treatment will be prescribed.

3

START OF PERSONALIZED TREATMENT

The treatment is tailored to each patient’s needs and may be administered through different routes (transdermal creams, oral medication, injections, etc.), always under strict medical and safety criteria.

The patient will receive precise instructions regarding dosage, duration, and follow-up of the treatment.

4

FOLLOW-UP AND THERAPEUTIC ADJUSTMENTS

Regular medical follow-up is essential, including blood tests every 3 months. In addition, 4–6 weeks after starting treatment, the medical team conducts a telephone consultation to assess clinical progress and the initial hormonal response.

These reviews allow for dose and administration route adjustments in order to optimize results and ensure safe and effective treatment.

WHY NEOLIFE?

At Neolife, we use hormone replacement or optimization therapy with bioidentical hormones—that is, hormones that are structurally and molecularly identical to those our body no longer produces or does not produce as effectively.

Our clinical rigor and more than 15 years of experience in these treatments, together with our constant focus on safety, enable us to personalize the most appropriate hormone replacement approach for each patient.

Our programs are based on current scientific evidence, randomized clinical trials, and related epidemiological studies, leaving no doubt about their efficacy and safety.

Our extensive multidisciplinary team is trained in Longevity – Age Management Medicine, a discipline based exclusively on scientific evidence and supported by our clinical experience.

Safety and Scientific Evidence

Hormone Replacement Therapy has long been at the center of controversy. Fortunately, current scientific evidence leaves no doubt regarding its efficacy and safety, although work remains to dispel preconceived notions and biases about its use—both in the public sphere and within the medical community.

In recent years, part of the debate surrounding the medical management of menopause has been influenced by the interpretation of certain clinical studies conducted in very specific contexts. Some of these studies analyzed populations with particular characteristics, such as older age groups or specific risk profiles, which led to conclusions that were later generalized excessively.

Critical analysis and subsequent review of these studies by the scientific community have made it possible to better understand the factors influencing the observed outcomes, as well as the importance of distinguishing between different patient profiles and clinical approaches.

Today, scientific literature and international clinical guidelines emphasize the need to address women’s health during menopause from an individualized perspective, based on comprehensive medical assessment, clinical context, and the best available evidence.

For this reason, it is essential to conduct a personalized evaluation that helps to understand the physiological changes characteristic of this stage and to support women in making informed decisions about their health, always within a rigorous and up-to-date medical framework.

n las últimas décadas se han publicado numerosos estudios clínicos y epidemiológicos que han permitido ampliar el conocimiento sobre el papel de la función hormonal en la salud a lo largo de la vida adulta. La evidencia científica actual subraya la importancia de una correcta valoración médica de estos procesos, especialmente en etapas de cambio fisiológico.

Durante años, determinadas interpretaciones simplificadas o extrapolaciones procedentes de otros contextos han generado preocupación en torno al impacto de la función hormonal sobre la salud prostática y cardiovascular. Sin embargo, el análisis riguroso de la literatura científica ha contribuido a matizar estas percepciones y a diferenciar entre situaciones clínicas muy distintas.

Today, there is growing consensus within the scientific community regarding the importance of maintaining appropriate hormonal balance as part of metabolic, bone, and cardiovascular health, as well as the need to address these aspects from an individualized, evidence-based medical perspective.

For this reason, a comprehensive clinical evaluation—supported by biomarkers and ongoing medical follow-up—is essential to understand overall health status and the factors that may influence aging and quality of life.

FREQUENTLY ASKED QUESTIONS ABOUT BIOIDENTICAL HORMONE REPLACEMENT THERAPY AT NEOLIFE

  • Yes, the use of bioidentical hormones—as opposed to synthetic ones—makes this therapy, when administered by experienced professionals, a highly effective and very safe treatment.

  • Intradermal
  • Intramuscular
  • Oral
  • Like any medical treatment, without exception, it has its contraindications. Before proceeding, Neolife will send you a specific questionnaire developed by our medical team, which includes certain absolute and relative contraindications, as well as other relevant information to determine whether you are a candidate for this therapy.

  • No, las mujeres obtienen un enorme beneficio, pero también los hombres pueden volver a tener niveles óptimos de su hormona sexual con este tratamiento, resolviendo así multitud de síntomas y problemas de salud tanto actuales como futuros.

FREQUENTLY ASKED QUESTIONS

MADRID

Velázquez, 14 – 28001 – Madrid

+34 91 732 59 50

MARBELLA

Calvario, 6 – 29601 – Málaga

+34 95 130 44 88

BARCELONA

Ferran Agulló, 8 – 08021 –  Barcelona

+34 93 193 51 62

THE BEST PROFESSIONALS AT YOUR SERVICE

WE HELP OUR PATIENTS FEEL BETTER AND STOP NOTICING THE EFFECTS OF AGING, SUCH AS MENOPAUSE